Ok, so I bought skyrim on steam and tried to install it via POL installer (I have 4.1.3).
It installed wine 1.5.4, vcrun's, .net's, dx runtime and everything. I did exactly what installer instructed.

So when I try to lunch skyrim, I hear sound but the renderer and window are broken.
http://shrani.si/f/3I/Qg/1epzyLhy/screenshot-from-2012-07-.png

Any ideas?

I tried under latest wine 1.5.8 same thing.

Actually game runs fine in fullscreen so nvm. Guess it wont work in windowed, not in gnome or xfce.