With wine it is possible now to run an emulator called Dolphin which can run Gamecube and Wii games.
In the second case on a native windows system it is also possible to use a real wiimote using via USB bluetooth stick, but that seems not to work in wine.
Could it be possible to allow the bluetooth stick to work under wine?
Would it be a good idea to develop a script for installing Dolphin and getting bluetooth enabled?
Wine doesn't support USB right now but it is one of the points in release plan You could also vote for a bug to show your interest in USB support.
As for the script you have to find someone to do it for you.
