Dont use DirectX 11. I have had nothing but problems. Off the top of my head, you will probably need a wine version that has the ubisoft patch for it, as well as install the following dependencies before you install the game:
VCRuntime 2008 (and maybe 2010? I do both most of the time)
d3dx9 and d3dx10
Mono 2.8 (.NET doesnt work for crap in wine. haha. )
Surprisingly enough, Mono has damn near full compatibility with .NET 3.5, at least from what I saw on their website, and honestly using mono 2.8 (and sometimes upper versions), I rarely see .net problems, and most of which I have been able to fix by switching a DLL here and there.
Also, check WineHQ.com's appDB, as im pretty sure its listed in there. I had AC2 running SO fly in linux. I broke it somehow, but it ran great. And I didnt use the POL Tie (or whatever its called) for it. Just installed by hand, using some of these dependency installs.
Almost every game that I see, especially now, will for SURE require vcruntime at least 2008 (some older games use 2005, but 2008 should work for 2005 compatible games), direct3d, and .NET (which we would use Mono for).